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            BioNOT is a searchable database of negated biomedical sentences (1). It consists of more than 58 million negated sentences from over 500 million indexed sentences and was built using the open source negation scope detection alorithm, NegScope (2).

 

The BioNOT database The BioNOT system was tested by looking at negated relations between genes and three genetic disorders (autism, Alzhiemer's disease and Parkinson's disease). 

 To use BioNOT, simply enter your query in the search box (for example MeCP2 autism). Search results with the negated sentence and the sentences preceding and following the negated sentences are displayed. A link to the source of the sentence is also provided, which links to the article from which the negated sentence was extracted.

 

1. Shashank Agarwal, Hong Yu "BioNOT: A searchable database of biomedical negated sentences" BMC Bioinformatics, 2011; 12:420-426. Link

2. Shashank Agarwal, Hong Yu "Biomedical negation scope detection with Conditional Random Fields" Journal of the American Medical Informatics Association (JAMIA), 2010; 17:696-701. Link

 

Project supported by NIH grant 1R01GM095476

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